A21, Deep Crystal Polish (20-71B): A2116
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Distillates (petroleum), hydrotreated light Dermal Mouse Some positive data exist, but the data are not
sufficient for classification
Kieselguhr, soda ash flux-calcined Not
specified.
Mouse Some positive data exist, but the data are not
sufficient for classification
Distillates (petroleum), hydrotreated middle Dermal Mouse Some positive data exist, but the data are not
sufficient for classification
Glycerin Ingestion Mouse Some positive data exist, but the data are not
sufficient for classification
Quartz Inhalation Human
and
animal
Carcinogenic.
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-
4-isothiazolin-3-one (3:1)
Dermal Mouse Not carcinogenic
Mixture of: 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-
4-isothiazolin-3-one (3:1)
Ingestion Rat Not carcinogenic
Reproductive Toxicity
Reproductive and/or Developmental Effects
Name Route Value Species Test result Exposure
Duration
Kieselguhr, soda ash flux-calcined Ingestion Not toxic to female reproduction Rat NOAEL 509
mg/kg/day
1 generation
Kieselguhr, soda ash flux-calcined Ingestion Not toxic to male reproduction Rat NOAEL 497
mg/kg/day
1 generation
Kieselguhr, soda ash flux-calcined Ingestion Not toxic to development Rat NOAEL
1,350
mg/kg/day
during
organogenesis
Glycerin Ingestion Not toxic to female reproduction Rat NOAEL
2,000
mg/kg/day
2 generation
Glycerin Ingestion Not toxic to male reproduction Rat NOAEL
2,000
mg/kg/day
2 generation
Glycerin Ingestion Not toxic to development Rat NOAEL
2,000
mg/kg/day
2 generation
Mixture of: 5-chloro-2-methyl-4-
isothiazolin-3-one and 2-methyl-4-
isothiazolin-3-one (3:1)
Ingestion Not toxic to female reproduction Rat NOAEL 10
mg/kg/day
2 generation
Mixture of: 5-chloro-2-methyl-4-
isothiazolin-3-one and 2-methyl-4-
isothiazolin-3-one (3:1)
Ingestion Not toxic to male reproduction Rat NOAEL 10
mg/kg/day
2 generation
Mixture of: 5-chloro-2-methyl-4-
isothiazolin-3-one and 2-methyl-4-
isothiazolin-3-one (3:1)
Ingestion Not toxic to development Rat NOAEL 15
mg/kg/day
during
organogenesis
Target Organ(s)
Specific Target Organ Toxicity - single exposure
Name Route Target Organ(s) Value Species Test result Exposure
Duration
Distillates (petroleum),
hydrotreated light
Inhalation central nervous
system depression
May cause drowsiness or
dizziness
NOAEL Not
available
Distillates (petroleum),
hydrotreated light
Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification
NOAEL Not
available
Distillates (petroleum),
hydrotreated middle
Inhalation central nervous
system depression |
respiratory irritation
Some positive data exist, but the
data are not sufficient for
classification
Not
available
NOAEL NA
Distillates (petroleum),
hydrotreated middle
Ingestion central nervous
system depression
May cause drowsiness or
dizziness
Not
available
NOAEL NA
Mixture of: 5-chloro-2-
methyl-4-isothiazolin-3-
one and 2-methyl-4-
isothiazolin-3-one (3:1)
Inhalation respiratory irritation Some positive data exist, but the
data are not sufficient for
classification
similar
health
hazards
NOAEL Not
available
(12 Seiten)
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